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You may cite ISE-MeshTools with the following
Lebrun, R. ISE-MeshTools, a 3D interactive fossil reconstruction freeware. 12th Annual Meeting of EAVP, Torino, Italy; 06/2014
Lebrun, R., Orliac, M. J., 2016. MorphoMuseuM: an online platform for publication and storage of virtual specimens. The Paleontological Society Papers, 22, 183-195. https://doi.org/10.1017/scs.2017.14
No. However, you can digitize 3D landmarks on complex 3D surfaces using ISE-MeshTools, which you can use in other software.
No. To extract 3D meshes CT/MRI data sets, you have to use another software. However, you can edit 3D Meshes in various ways using ISE-MeshTools.
I did not implement yet the possibility to cancel any action. I am thinking about it though. So remember to regularly save your work (especially when tagging surfaces), otherwise precious hours of work can be lost in a second.